Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

91
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
91

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-read Sequencing: from Complete Molecules to Context-resolved Biology.

Genomics, proteomics & bioinformatics·2026
Same author

Amaranth: enhanced single-cell transcript assembly via discriminative modelling of UMI reads and internal reads.

Bioinformatics (Oxford, England)·2026
Same author

Local brain network alterations in prodromal and De Novo Parkinson's disease: basal ganglia functional connectivity mediates the association between regional homogeneity and motor manifestations.

Behavioral and brain functions : BBF·2026
Same author

Ultra-high-field 7T MRI reveals neural abnormalities of attention networks in relation to cognitive impairment in hypertension.

Brain research·2026
Same author

The response of the bacterial community to long-term pollution in coastal sediment cores.

Marine environmental research·2026
Same author

Personalized high-dose accelerated intermittent theta-burst stimulation improves cognitive function in mild Alzheimer's disease: A randomized sham-controlled trial.

Brain stimulation·2026

Related Experiment Video

Updated: May 6, 2026

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
08:17

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

15.4K

Harnessing Nanomaterials for Precision Intracellular Sensing.

Yi Xing1, Jinyan Cui1, Nicholas Nedved2

  • 1Department of Chemistry, Indiana University, Bloomington, Indiana 47405, United States.

JACS Au
|August 1, 2025
PubMed
Summary
This summary is machine-generated.

Nanomaterials offer advanced tools for studying intracellular signaling dynamics. These nanoscale innovations provide high-resolution insights into cell communication, advancing biological understanding and disease research.

Keywords:
intracellular sensinglive-cell imagingnanomaterialsnanosensorsorganelle imagingquantitative cell biologysubcellular imaging

More Related Videos

Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

13.4K
Harmonic Nanoparticles for Regenerative Research
09:23

Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

11.8K

Related Experiment Videos

Last Updated: May 6, 2026

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems
08:17

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

15.4K
Self-reporting Scaffolds for 3-Dimensional Cell Culture
14:49

Self-reporting Scaffolds for 3-Dimensional Cell Culture

Published on: November 7, 2013

13.4K
Harmonic Nanoparticles for Regenerative Research
09:23

Harmonic Nanoparticles for Regenerative Research

Published on: May 1, 2014

11.8K

Area of Science:

  • Cell Biology
  • Biophysics
  • Nanotechnology

Background:

  • Cells utilize intracellular signaling pathways involving ions, biomolecules, and organelles for communication.
  • Current understanding of signaling dynamics, coordination, and spatial-temporal sequences is limited.
  • Traditional methods lack the real-time, high-resolution capabilities needed for comprehensive analysis.

Purpose of the Study:

  • To explore the application of nanomaterials in probing intracellular signaling.
  • To highlight how nanomaterial innovations enhance quantitative, high-resolution insights into cellular communication.
  • To discuss challenges and opportunities in using nanomaterials for studying signaling pathways.

Main Methods:

  • Utilizing nanomaterials for nanoscale precision in sensing and imaging.
  • Employing multiplexed sensing capabilities of nanomaterials.
  • Real-time monitoring and manipulation of intracellular signaling events.

Main Results:

  • Nanomaterials provide unprecedented spatial resolution and sensitivity for studying signaling.
  • Real-time data acquisition reveals dynamic signaling activities previously unobserved.
  • Quantitative insights into the timing and coordination of molecular interactions are becoming accessible.

Conclusions:

  • Nanomaterial innovations are transforming the study of intracellular signaling.
  • This technology advances fundamental cell biology and understanding of disease mechanisms.
  • Further development is needed to fully address remaining challenges and unlock future opportunities.