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A Microfluidics Approach for the Functional Investigation of Signaling Oscillations Governing Somitogenesis
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From genes to patterns: five key dynamical systems concepts to decode developmental regulatory mechanisms.

Usha Kadiyala1, David Sprinzak2, Nicholas A M Monk3,4

  • 1Department of Biophysics, University of Michigan, Ann Arbor, MI 48109, USA.

Development (Cambridge, England)
|August 1, 2025
PubMed
Summary

Dynamical systems theory offers a quantitative framework to understand developmental biology. This approach illuminates cell fate decisions and pattern formation by analyzing concepts like switches, noise, and oscillations.

Keywords:
Developmental dynamicsDynamical systemsModellingSignallingWaddington landscape

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