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A Practical Guide to Behavioral Treatment for Children with Disorders of Gut-Brain Interaction

Jessica Buzenski1, Stephanie Davenport2, Amanda Glinky3

  • 1Department of Pediatrics, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, USA.

Gastroenterology Clinics of North America
|August 2, 2025
PubMed

Insights

Disorders of Gut-Brain Interaction (DGBI) significantly impact children

Area of Science:

  • Pediatric Gastroenterology
  • Neurogastroenterology
  • Child Psychology

Background:

  • Disorders of Gut-Brain Interaction (DGBI) are prevalent in children.
  • These conditions significantly affect the quality of life for both children and their caregivers.
  • Current management often requires a comprehensive approach.

Purpose of the Study:

  • To highlight the importance of a biopsychosocial approach in managing pediatric DGBI.
  • To emphasize treatments targeting the gut-brain axis.
  • To advocate for improved access and acceptance of specialized care.

Main Methods:

  • Screening for biological and environmental triggers.
  • Implementing treatments focused on the gut-brain axis.
  • Utilizing a psychogastroenterology specialist model.

Main Results:

  • Biopsychosocial interventions targeting the gut-brain axis show significant symptom improvement.
  • Specialized care can lead to better outcomes for various gastrointestinal diseases.
  • The approach addresses the complex interplay of factors in DGBI.

Conclusions:

  • A biopsychosocial framework is essential for treating pediatric DGBI.
  • Gut-brain axis-targeted therapies offer substantial benefits.
  • Increased acceptance and accessibility of psychogastroenterology are crucial for advancing care.

Keywords:
Biopsychosocial modelCognitive behavioral therapyConstipationDisorders of gut brain interactionIrritable bowel syndromePediatricsPsychogastroenterologyRumination

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