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Does Cluster-Robust Estimation Provide Within-Study Effects? A Comparison of Individual Participant Data Methods in
Lennert J Groot1, Kees Jan Kan1, Suzanne Jak1
1University of Amsterdam.
Cluster-robust estimation in individual participant data meta-analysis (IPD MASEM) can distort findings by misrepresenting within-study effects and standard errors. Careful selection of IPD MASEM methods is crucial for accurate results.
Area of Science:
- Psychometrics
- Statistical Modeling
- Meta-Analysis
Background:
- Individual participant data meta-analysis (IPD MASEM) offers advanced modeling capabilities.
- Several methods exist for IPD MASEM, including cluster-robust estimation, two-level SEM, and One-Stage MASEM (OSMASEM).
- Cluster-robust estimation is popular but may produce divergent results compared to other techniques.
Purpose of the Study:
- To compare the performance of different IPD MASEM methods.
- To evaluate the accuracy and biases associated with cluster-robust estimation versus other approaches.
- To provide guidance on selecting appropriate IPD MASEM methods.
Main Methods:
- The study employed simulated data for meta-analytical structural equation modeling (MASEM).
- Simulations varied key factors: intraclass correlations, parameter equality, number of studies, and missing data.
- Performance was assessed by comparing within-study estimates, standard errors, and model fit across methods.
Main Results:
- Cluster-robust estimation frequently misrepresented within-study estimates.
- Biased standard errors were commonly observed with cluster-robust estimation.
- Cluster-robust estimation tended to incorrectly reject model fit more often than other methods.
Conclusions:
- Cluster-robust estimation may not be suitable for all IPD MASEM applications due to potential biases.
- The findings underscore the importance of method selection in IPD MASEM.
- Researchers should carefully consider alternative methods to ensure accurate meta-analytical structural equation modeling.
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