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Updated: Sep 12, 2025

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A calix[4]pyrrole functionalized with an amidoindole ester for the selective recognition of the dihydrogen phosphate
Ju Hyun Oh1, Sang Kyu Shin1, Sung Kuk Kim1
1Department of Chemistry, College of Natural Sciences, Gyeongsang National University, Jinju 52828, Korea. sungkukkim@gnu.ac.kr.
Abstract:
A bisamidoindole ester-functionalized calix[4]pyrrole (2), which features additional hydrogen bond donors and acceptors, complexes dihydrogen phosphate (H2PO4-) with high affinity and selectivity. This binding takes place via distinct modes compared to those observed for meso-pyrrolic calix[4]pyrrole 1 and the parent calix[4]pyrrole, underscoring the impact of strategic functionalization on anion binding geometry and selectivity.
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