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Updated: Sep 12, 2025

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Monitoring Ovarian Stimulation for Assisted Reproduction With Patient Self-Scans Using a Home Vaginal Ultrasound

Yoel Shufaro1,2, Mor Cohen1, Avital Wertheimer1,2

  • 1Infertility and in vitro fertilization (IVF) Unit, Beilinson Hospital, Rabin Medical Center, 39 Jabotinsky Street, Petah Tikva, 4941492, Israel.

Journal of Medical Internet Research
|August 6, 2025
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Summary

Home self-scans using a vaginal ultrasound device (FC) are reliable for monitoring ovarian stimulation, showing strong correlation with in-clinic (IC) sonographies. This technology offers a feasible alternative for fertility treatments.

Keywords:
follicle monitoringhome sonographyin-vitro fertilizationmobile phoneself vaginal sonography

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Area of Science:

  • Reproductive endocrinology and infertility
  • Medical imaging and diagnostics
  • Ultrasound technology applications

Background:

  • Ovarian follicle and endometrial thickness monitoring are crucial but burdensome for assisted reproduction patients and clinics.
  • Home-based self-scans using ultrasound devices offer a potential solution to reduce patient and clinic burden.

Purpose of the Study:

  • To evaluate the reliability of vaginal self-scans with a smartphone-based device (FC) compared to in-clinic (IC) sonographies.
  • To assess the feasibility of home-based monitoring during ovarian stimulation for in-vitro fertilization or fertility preservation.

Main Methods:

  • A prospective, interventional study involving 44 patients undergoing ovarian stimulation for IVF.
  • Patients performed vaginal self-scans using a home ultrasound device with remote sonographer guidance.
  • Comparison of image quality, endometrial thickness, and follicle measurements between home (FC) and in-clinic (IC) scans.

Main Results:

  • Home scans demonstrated suitable image quality and closely matched IC findings for antral follicle count (ρ=0.86), stimulated follicles (ρ=0.84), and leading follicle identification (87%).
  • High correlation was observed for aspirated oocyte numbers (ρ=0.82), mature oocyte ratios (ρ=0.88), and endometrial thickness (ρ=0.54) between FC and IC.
  • 82% of patients and 91% of sonographers expressed satisfaction and interest in future use of the home ultrasound device.

Conclusions:

  • The home ultrasound device (FC) is feasible, comparable, and well-correlated with standard in-clinic (IC) scans for monitoring follicular development.
  • This technology provides a basis for remote, home-based monitoring during ovarian stimulation, potentially applicable to milder stimulations and natural cycles.