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The Association Between ABO Blood Groups and Adenomyosis
Sunita Pun1, Neebha Ojha1, Poonam Koirala1
1Department of Obstetrics and Gynecology, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
Women with blood group B have a higher risk of adenomyosis, while blood group A may be protective. Further research is needed to confirm these ABO blood group associations with adenomyosis risk.
Area of Science:
- Reproductive Medicine
- Genetics
- Epidemiology
Background:
- Limited evidence exists on the association between ABO blood groups and adenomyosis.
- This study addresses the knowledge gap by investigating this relationship in Nepalese women.
Purpose of the Study:
- To investigate the association between ABO blood groups and the risk of developing adenomyosis.
- To identify potential risk factors for adenomyosis based on blood type.
Main Methods:
- A cross-sectional study was conducted at Tribhuvan University Teaching Hospital.
- Statistical analysis included odds ratios, 95% confidence intervals, and P-values (P<0.05 considered significant).
Main Results:
- Of 249 women, 85 (34%) had confirmed adenomyosis.
- Blood group B showed a significantly increased risk (OR=2.3, P=0.01).
- Blood group A showed a significantly reduced risk (OR=0.41, P=0.03).
Conclusions:
- Blood group B is associated with a 2.3-fold higher risk of adenomyosis.
- Blood group A may offer a protective effect against adenomyosis.
- Larger, multicenter studies are recommended to validate these findings.
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