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Related Concept Videos

Epigenetic Regulation01:37

Epigenetic Regulation

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Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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What is Climate?01:16

What is Climate?

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Climate refers to the prevailing weather conditions in a specific area over an extended period. As the saying goes, “Climate is what you expect. Weather is what you get.” Climate is influenced by geographic factors, such as latitude, terrain, and proximity to bodies of water.
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Natural Selection and Adaptation01:15

Natural Selection and Adaptation

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Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
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Transcription01:10

Transcription

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Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
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Responses to Heat and Cold Stress02:45

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Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
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Updated: Sep 12, 2025

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain
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Epigenetic Plasticity Is Likely to Exacerbate Climate Change Vulnerability.

Bing Chen1, Yiyong Chen2, Aibin Zhan2

  • 1Ministry of Education Key Laboratory for Biodiversity Science and Ecological Engineering, Institute of Biodiversity Science, Center for Evolutionary Biology, School of Life Sciences, Fudan University, Shanghai, China.

Global Change Biology
|August 8, 2025
PubMed
Summary
This summary is machine-generated.

Epigenetic plasticity influences species' climate change vulnerability. While plasticity alone increases risk, migration can mitigate this, offering crucial insights for biodiversity conservation and evolutionary studies.

Keywords:
DNA methylationclimate changeepigeneticsplasticityvulnerability

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Area of Science:

  • Evolutionary biology
  • Climate change ecology
  • Genetics and epigenetics

Background:

  • Climate change poses a significant threat to global biodiversity.
  • Adaptation and migration are key evolutionary processes studied in response to environmental change.
  • The role of phenotypic plasticity in mediating species' responses to climate change is underexplored.

Purpose of the Study:

  • To investigate the influence of epigenetic plasticity on the climate change vulnerability of threespine stickleback (Gasterosteus aculeatus).
  • To compare the effects of plasticity and migration on species' responses to projected climate scenarios.
  • To advance range modeling by integrating plasticity into predictions of species' responses to environmental change.

Main Methods:

  • Estimation of epigenetic plasticity's influence on threespine stickleback responses to climate change.
  • Modeling of species vulnerability under projected climates, considering the availability of plastic loci.
  • Assessment of the mitigating effect of short-distance migration on climate change vulnerability.

Main Results:

  • Vulnerability to projected climates was highest when only plastic loci were available to populations.
  • Short-distance migration was found to mitigate the increased vulnerability caused by reliance on plasticity alone.
  • Epigenetic modifications play a crucial role in mediating both evolved and plastic responses to environmental change.

Conclusions:

  • Epigenetic plasticity is a critical factor in species' persistence under climate change.
  • The interplay between plasticity and migration significantly shapes species' responses to changing environments.
  • Incorporating plasticity into ecological models provides a more comprehensive understanding of species' future distributions.