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Updated: Jul 25, 2026

Neuromodulation and Mitochondrial Transport: Live Imaging in Hippocampal Neurons over Long Durations
Published on: June 17, 2011
A NAD(P)H-driven mitochondria-to-nucleus probe for dual-organelle imaging in dopaminergic toxicity models
Qu Tang1, Bin Jiang2, Majun Yang1
1School of Public Health, Key Laboratory of Jiangsu Higher Education Institutions for Advanced Medical Analytics and Public Health, Nantong Key Laboratory of Public Health and Medical Analysis, Nantong University, 9 Seyuan road, Nantong 226019, P. R. China. wangqi@ntu.edu.cn.
Abstract:
A novel dual-functional fluorescent probe was developed enabling real-time tracking of intracellular NAD(P)H flux and mitochondrial functional decline at the single-cell level with high precision. This probe could assess mitochondrial damage and energy metabolism disruptions in PD-related dopaminergic toxicity models.

