Related Experiment Video
Updated: Sep 12, 2025

Employing Digital Droplet PCR to Detect BRAF V600E Mutations in Formalin-fixed Paraffin-embedded Reference Standard Cell Lines
Published on: October 8, 2015
Inference of Genetic Ancestry from Cancer-Derived Molecular Data with RAIDS
Pascal Belleau1,2, Astrid Deschênes2, David A Tuveson2
1Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring, NY, USA.
Abstract:
There has recently been increasing appreciation of ancestral effects on cancer genotypes and phenotypes. Consequently, the need has grown for ancestry annotation of cancer-derived molecular data. In response, we created a computational tool termed RAIDS (Robust Ancestry Inference using Data Synthesis). RAIDS is designed to infer genetic ancestry using as input sequence data from a variety of molecular protocols, even in the absence of matching cancer-free genotypes of the patient. Implemented as an R language package, RAIDS is available from the Bioconductor repository. Here we describe functionalities of RAIDS, provide instructions for its installation, give examples of its usage, and explain the interpretation of its output. While RAIDS is being actively developed, the guidance provided here is expected to apply to future refined and expanded versions of this software tool.
More Related Videos
07:41Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
08:15gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
Published on: October 6, 2014
Related Concept Videos
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Evolutionary Relationships through Genome Comparisons
Modern Molecular Taxonomy
Applications of Molecular Taxonomy
Cancer Survival Analysis
DNA Microarrays