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Generation of two B2M knockout induced pluripotent stem cell lines (DHMi005-A-8 and DHMi005-A-9) using CRISPR/Cas9

Katharina Abdel-Malek1, Franziska von Eisenhart-Rothe1, Santiago Stiegmann1

  • 1Department of Cardiovascular Surgery, Institute Insure, TUM University Hospital German Heart Center, TUM School of Medicine & Health, Technical University of Munich, Germany.

Stem Cell Research
|August 10, 2025
PubMed

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Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced Short...
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