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Sex-Specific Facial-Soft-Tissue Morphology in Mandibular Prognathism: A Homologous-Model Analysis
Nobuhide Shibusawa1,2, Tomohiro Yamada2, Kousuke Yasuda2
1Department of Maxillofacial Diagnostic and Surgical Sciences, Division of Oral and Maxillofacial Surgery, Graduate School of Dental Science, Kyushu University, Fukuoka, Japan.
The Journal of Craniofacial Surgery
|August 11, 2025
Summary
Facial surgery for mandibular prognathism shows sex differences. Males achieve results similar to healthy males, but females retain some masculine features, suggesting tailored surgical approaches are needed for optimal esthetics.
Area of Science:
- Craniofacial Surgery
- Orthognathic Surgery
- Facial Soft Tissue Analysis
Background:
- Mandibular prognathism presents unique challenges in facial soft tissue morphology.
- Understanding sex-specific differences is crucial for effective treatment planning in orthognathic surgery.
Purpose of the Study:
- To evaluate sex differences in facial soft tissue morphology in patients with mandibular prognathism.
- To assess the outcomes of bilateral sagittal split ramus osteotomy (SSRO) considering these sex differences.
- To determine if surgical outcomes differ between males and females with mandibular prognathism.
Main Methods:
- Inclusion of 30 patients (15 males, 15 females) with mandibular prognathism and 30 healthy controls (15 males, 15 females).
- Collection of three-dimensional facial data and analysis using homologous modeling.
- Application of principal component analysis (PCA), analysis of variance (ANOVA), and Tukey's test for qualitative and quantitative assessments.
Main Results:
- Males exhibited greater facial height and longer chins compared to females.
- Females presented with smaller chins and a more rounded zygomatic-cheek area.
- Postoperative male patients' facial morphology approximated that of healthy males, while females retained features like midface flatness and increased facial height.
Conclusions:
- Surgical outcomes for mandibular prognathism vary between sexes.
- Female patients may require additional midface and chin surgical interventions for improved esthetics and satisfaction.
- Tailoring orthognathic surgery based on sex-specific facial morphology is essential for optimal patient outcomes.

