Identification and quantification of intentionally and non-intentionally added substances occurring from...

The migration of various compounds from packaging material to foodstuffs presents a multifaceted confrontation with involvement for food safety and human health. This review examines the different migration mechanisms and factors that influence migration including nature of the food, type and extent of contact, temperature and duration of contact, external humidity and migrant polarity, mobility of the substances in the packaging, nature of packaging material, migrant characteristics and concentration in packaging. Advanced analytical methods for monitoring of migrating compounds were discussed comprehensively. Furthermore, the identification and quantification of intentionally and non-intentionally added substances (IAS and NIAS, respectively) occurring from biodegradable food packaging were analyzed in terms of polymer matrix where IAS and NIAS were added, analytical method/technique for monitoring IAS and NIAS, along with migration parameters (test conditions, food simulants, and foodstuffs that had a direct contact with the IAS and NIAS of packaging).