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Published on: May 21, 2019
Tetralone Formation through Visible-Light-Driven Photocyclization of Aryl Sulfoxonium Ylides with Unactivated Alkenes
Ning Xian1, Zihao Li1, Xiaochen Ji1
1Key Laboratory of Environmentally Friendly Chemistry and Application of Ministry of Education, College of Chemistry, Xiangtan University, Xiangtan, Hunan 411105, China.
Abstract:
Herein, we report a visible-light-driven photoredox [4+2] cycloaddition of sulfoxonium ylides with alkenes for the modular assembly of value-added γ-substituted tetralone scaffolds under mild and metal-free conditions. This protocol exhibits an extremely broad functional group tolerance and good selectivity. Mechanistic investigations suggest the involvement of sulfoxonium ylide radical cations and the 1,4-hydride shift process in this photochemical system.
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