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Updated: Sep 11, 2025

Transoral Robotic Total Thyroidectomy and Bilateral Central Regional Lymph Node Dissection for Papillary Thyroid Carcinoma
Published on: September 15, 2023
Protection of parathyroid function during thyroid surgery with a complete intermediate approach: a retrospective
Jianming Yuan1, Jianhua Gu2, Min Ding1
1Department of General Surgery, RuiJin Hospital Lu Wan Branch, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
The complete intermediate surgical approach for thyroidectomy better preserves parathyroid function than the traditional lateral approach, reducing permanent hypoparathyroidism risk. This method improves postoperative parathyroid hormone and calcium levels.
Area of Science:
- Endocrine Surgery
- Surgical Oncology
- Thyroid Surgery
Background:
- Iatrogenic parathyroid injury is a risk during thyroid surgery.
- The lateral approach is traditional, while the complete intermediate approach is gaining traction.
- Comparing these approaches for parathyroid function is crucial.
Purpose of the Study:
- To compare the effects of the complete intermediate approach versus the traditional lateral approach on postoperative parathyroid function.
- To evaluate the incidence of iatrogenic parathyroid injury between the two surgical methods.
Main Methods:
- A study of 270 papillary thyroid cancer patients undergoing total thyroidectomy.
- Patients were divided into complete intermediate (observation) and traditional lateral (control) groups.
- Parathyroid hormone and calcium levels were monitored for 6 months post-surgery.
Main Results:
- No significant preoperative differences in parathyroid hormone or calcium levels between groups.
- Postoperative parathyroid hormone and calcium levels were higher in the intermediate approach group.
- The intermediate approach group showed full recovery, while 4 control patients developed permanent hypoparathyroidism.
Conclusions:
- The complete intermediate approach offers superior protection of parathyroid function compared to the traditional lateral approach.
- This method significantly reduces the incidence of iatrogenic parathyroid injury after thyroidectomy.
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