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Updated: Sep 11, 2025

Measuring Relative Insulin Secretion using a Co-Secreted Luciferase Surrogate
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Fully closed-loop control with ultra-rapid versus standard insulin lispro: A randomised crossover study simulating

Hood Thabit1,2, Jonathan Lim1, Malgorzata E Willinska3,4

  • 1Manchester Diabetes Centre, Manchester Royal Infirmary, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.

Diabetic Medicine : a Journal of the British Diabetic Association
|August 15, 2025
PubMed
Summary

Ultra-rapid insulin lispro (URIL) showed a trend toward better glucose control in a closed-loop system, even without a meal bolus. Faster-acting insulins are key for future improvements in automated insulin delivery.

Keywords:
insulin analoguesinsulin deliverytype 1 diabetes

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