Nipple adenoma; a literature review and our experience with a rare feature

With this review, we aimed to contribute to the literature by reviewing the studies on nipple adenoma and presenting a novel study regarding its occurrence in a male case, for which we have not found any publications worldwide. We have reviewed studies on nipple adenoma, which we rarely encounter in the literature. We also present a 41-year-old male patient, whom we operated on with a diagnosis of nipple adenoma. His postoperative histopathological examination revealed invasive breast carcinoma, a unique case in the literature, together with this review study. Nipple adenoma, which is extremely rare in male patients, is rare in the literature and clinical practice. In light of the data, this case is the second instance of a male patient with nipple adenoma presented in the literature after many years. The fact that it is the only male patient associated with invasive carcinoma makes the case unique. Nipple adenomas require careful examination because they are rare and can be confused with malignancy. Moreover, although its association with malignancy is exceptionally rare, it should still be included in the differential diagnosis for male breast lesions. Safe surgery and postoperative follow-up are recommended.