![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
Non-FDG PET/CT imaging of inflammatory arthritis
Rodolfo Núñez1, Michael Reso2, Daichi Hayashi2
1Department of Radiology, Tufts Medical Center, Tufts University School of Medicine, 800 Washington St. # 299, Boston, MA, 02111, USA. rnunez1@tuftsmedicalcenter.org.
Skeletal Radiology
|August 15, 2025
Summary
Non-FDG PET/CT imaging offers objective evaluation for inflammatory arthritis, aiding diagnosis and treatment response assessment. This advanced imaging supports personalized medicine for better patient outcomes.
Area of Science:
- Nuclear Medicine
- Radiology
- Rheumatology
Background:
- Inflammatory arthritis causes significant disability and societal burden.
- Conventional imaging aids assessment, but objective, reproducible methods are needed.
- Personalized medicine requires precise evaluation of disease activity and treatment response.
Purpose of the Study:
- To review the potential applications of non-FDG PET/CT imaging in inflammatory arthritis.
- To explore how non-FDG PET/CT can assess the inflammatory cascade.
- To discuss new technical developments in PET/CT for inflammatory arthritis.
Main Methods:
- Narrative review of existing literature on PET/CT in inflammatory arthritis.
- Focus on non-FDG radiopharmaceuticals beyond FDG-PET/CT.
- Discussion of technical advancements in PET/CT imaging.
Main Results:
- FDG-PET/CT has shown clinical benefits but faced slow adoption.
- Non-FDG PET/CT can evaluate various aspects of the inflammatory process.
- Emerging technologies promise enhanced diagnostic capabilities.
Conclusions:
- Non-FDG PET/CT imaging holds significant potential for inflammatory arthritis assessment.
- This modality can provide objective data for diagnosis and monitoring.
- Future developments may further refine its role in personalized patient care.
Keywords:
Future trendsInflammatory arthritisNarrative reviewNon-FDG PET/CT imagingPET/MRITotal body PETMore Related Videos
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