Containerless-Processing Bioactive Glass for Tissue Regeneration and Disease Therapy.

Area of Science:

• Biomaterials Science
• Materials Engineering
• Biomedical Engineering

Background:

• Bioactive glass (BG) is crucial for tissue repair due to its bioactivity and tunable properties.
• Conventional BG preparation methods face challenges in compositional design, contamination, and structural uniformity, limiting precise functionalization.
• Containerless processing presents a promising alternative for innovative BG preparation.

Purpose of the Study:

• To systematically review the limitations of traditional bioactive glass preparation techniques.
• To introduce the principles and advantages of containerless processing for bioactive glass.
• To present design strategies and applications of containerless-processing bioactive glass (CPBG).

Main Methods:

• Systematic summarization of traditional bioactive glass preparation bottlenecks.
• Introduction to the core principles of containerless technology.
• Review of design strategies and application directions for CPBG.

Main Results:

• Identified key limitations in conventional bioactive glass synthesis.
• Highlighted the advantages of containerless processing for composition and function design.
• Presented design strategies for CPBG in three application areas.

Conclusions:

• Containerless processing provides a novel pathway for advanced bioactive glass preparation.
• Research on containerless-processing bioactive glass (CPBG) is in its early stages but shows significant potential.
• This review bridges the gap between advanced glass technology and biomedical applications.