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Suppurative Stomatitis [Cheilitis Glandularis]: an underreported entity.
J-C Panico1, B-A Andrade, J Lazos
1Oral Medicine Department Facultad de Odontologia, Universidad Nacional de Córdoba Haya de la Torre SN. Ciudad Universitaria PC 5000. Córdoba, Argentina ggilligan@unc.edu.ar.
Medicina Oral, Patologia Oral Y Cirugia Bucal
|August 16, 2025
Summary
Stomatitis and Cheilitis Glandularis are rare inflammatory salivary gland disorders. This case series suggests hyposalivation may be an early factor in their multifactorial development.
Area of Science:
- Oral Medicine
- Pathology
- Salivary Gland Disorders
Background:
- Stomatitis and Cheilitis Glandularis are uncommon inflammatory conditions affecting minor salivary glands.
- The etiology remains uncertain, but local factors and systemic comorbidities linked to hyposalivation may play a role.
Purpose of the Study:
- To retrospectively analyze a case series of Stomatitis and Cheilitis Glandularis.
- To review clinical and epidemiological variables and discuss diagnostic criteria.
Main Methods:
- Retrospective analysis of six cases from Oral Diagnosis Centers in Argentina and Brazil.
- Cases were selected based on Reiter et al criteria.
- Demographic, clinicopathological features were described, and literature was reviewed.
Main Results:
- Six patients (4 males, 2 females, average age 65.33) were included.
- Most patients had comorbidities or medications associated with hyposalivation.
- Clinical findings included firm nodules and pus discharge; histopathology showed sialoadenitis and oncocytic metaplasia.
Conclusions:
- Stomatitis and Cheilitis Glandularis are challenging oral disorders.
- Hyposalivation may be an early phenomenon in a multifactorial context.
- Further research is necessary for a comprehensive understanding.
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