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Personalist Bioethics as a Guide to Assessing Emerging Anti-aging Therapies.

Ana Rodríguez-Díaz1, Esperanza Marín-Conde1, Lucia Gómez-Tatay1

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Aging is a malleable process, not inevitable. Current research suggests only nutritional interventions are ethically acceptable anti-aging therapies, while drugs and gene therapies pose significant risks.

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Aginganti-aging therapiesbioethicsgene therapylongevitynutritional interventionspersonalismpharmacological interventions

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Area of Science:

  • Gerontology and Bioethics
  • Exploration of aging as a modifiable biological process.

Background:

  • The traditional view of aging as inevitable is being challenged by scientific evidence.
  • Emerging therapies aim to modify the aging process, necessitating ethical evaluation.

Purpose of the Study:

  • To classify and evaluate promising anti-aging therapies based on bioethical implications.
  • To assess the ethical acceptability of nutritional, pharmacological, and gene therapies for aging.

Main Methods:

  • Classification of anti-aging interventions into nutritional, pharmacological, and gene therapy groups.
  • Analysis of mechanisms of action, risks, and benefits for each therapy group.
  • Ethical evaluation using principles of personalist bioethics.

Main Results:

  • Nutritional interventions are currently deemed ethically acceptable for anti-aging.
  • Pharmacological and gene therapies are in early development stages and pose risks to human life.
  • Ethical assessment indicates significant concerns regarding the safety and licitness of drug and gene therapies.

Conclusions:

  • Only nutritional interventions are ethically permissible anti-aging therapies at present.
  • Pharmacological and gene therapies require further development due to safety and ethical concerns.
  • Recommendations focus on healthy dietary control to manage aging-related frailty.