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Melanonychia: A Challenging Green Nail Syndrome Case Report
Kyoko Sugioka1, Tomoko Akeda1, Keiichi Yamanaka1
1Department of Dermatology Mie University Graduate School of Medicine Tsu Mie Japan.
Clinical Case Reports
|August 20, 2025
Summary
Green Nail Syndrome, a nail discoloration from Pseudomonas aeruginosa infection, can affect multiple nails. Topical nadifloxacin effectively treated this condition.
Area of Science:
- Medical Microbiology
- Dermatology
- Infectious Diseases
Background:
- Nail dyschromia is a change in nail color.
- Pseudomonas aeruginosa is a common bacterium.
- Green Nail Syndrome is a specific type of nail discoloration.
Purpose of the Study:
- To describe Green Nail Syndrome caused by Pseudomonas aeruginosa.
- To evaluate the effectiveness of topical nadifloxacin treatment.
Main Methods:
- Case observation of patients with Green Nail Syndrome.
- Clinical assessment of nail dyschromia.
- Application of topical nadifloxacin for treatment.
Main Results:
- Pseudomonas aeruginosa infection was identified as the cause of nail dyschromia.
- The condition typically affected one to two nails, but could involve more.
- Topical nadifloxacin demonstrated efficacy in treating the infection and resolving dyschromia.
Conclusions:
- Pseudomonas aeruginosa is a causative agent of Green Nail Syndrome.
- Topical nadifloxacin is an effective treatment option for this condition.
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