Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Spectroscopy of Carboxylic Acid Derivatives01:26

Spectroscopy of Carboxylic Acid Derivatives

2.5K
Infrared spectroscopy is primarily used to determine the types of bonds and functional groups. In carboxylic acid derivatives, a typical carbonyl bond absorption is observed around 1650–1850 cm−1. For esters, the absorption is recorded at around 1740 cm−1, while acid halides show the absorption at about 1800 cm−1. Another acid derivative, the acid anhydrides, exhibit two carbonyl absorption around 1760 cm−1 and 1820 cm−1, arising from the symmetrical and...
2.5K
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.2K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.2K
IR Spectrum Peak Splitting: Symmetric vs Asymmetric Vibrations01:08

IR Spectrum Peak Splitting: Symmetric vs Asymmetric Vibrations

1.2K
Identical bonds within a polyatomic group can stretch symmetrically (in-phase) or asymmetrically (out-of-phase). Similar to hydrogen bonding, these vibrations also influence the shape of the IR peak. Generally, asymmetric stretching frequencies are higher than symmetric stretching frequencies. For example, primary amines exhibit two distinct IR peaks between 3300–3500 cm−1 corresponding to the symmetric and asymmetric N-H stretching, while secondary amines exhibit a single...
1.2K
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)01:19

2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)

906
Heteronuclear single-quantum correlation spectroscopy (HSQC) is a 2D NMR technique that reveals one-bond correlations between hydrogen and a heteronucleus. The HSQC experiment is similar to the heteronuclear correlation experiment (HETCOR) but is more sensitive. In the HSQC spectrum, the proton chemical shift is plotted on the horizontal F2 axis, while the 13C chemical shift is plotted on the vertical F1 axis. The corresponding proton and 13C spectra are also shown. The HSQC contour plot does...
906
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

598
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
598
VSEPR Theory and the Basic Shapes02:52

VSEPR Theory and the Basic Shapes

70.6K
Overview of VSEPR Theory
70.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simultaneous measurement of piperacillin, tazobactam and meropenem in patient samples using LC-MS/MS to support β-lactam therapeutic drug monitoring.

Analytical methods : advancing methods and applications·2026
Same author

Quantitative Lateral Flow Assay for Meropenem Determination: A Proof-of-Concept Study.

ACS omega·2025
Same author

Development of a novel quantitative lateral flow assay for vancomycin for therapeutic drug monitoring.

Scientific reports·2025
Same author

Does anticancer therapy directly contribute to antimicrobial resistance?

The Lancet. Microbe·2025
Same author

AI-Based Computational Methods in Early Drug Discovery and Post Market Drug Assessment: A Survey.

IEEE transactions on computational biology and bioinformatics·2024
Same author

Mechanism-Based Pharmacokinetic/Pharmacodynamic Model of Voriconazole for Predicting the Clinical Outcomes of Adult Patients With Invasive Aspergillosis.

Therapeutic drug monitoring·2024
Same journal

Relation DETR+: Exploring Explicit Position Relation Prior for Dense Prediction.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

RBF++: Quantifying and Optimizing Reasoning Boundaries across Measurable and Unmeasurable Capabilities for Chain-of-Thought Reasoning.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

CAFE: Cross-View Adaptive Fusion and Cluster Center Enhancement for Robust Multi-View Clustering.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

DIVER: Reinforced Diffusion Breaks Imitation Bottlenecks in End-to-End Autonomous Driving.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Ethics-Aware Safe Reinforcement Learning for Rare-Event Risk Control in Interactive Urban Driving.

IEEE transactions on pattern analysis and machine intelligence·2026
Same journal

Learning Shape Anchors for Holistic Indoor Scene Understanding.

IEEE transactions on pattern analysis and machine intelligence·2026
See all related articles

Related Experiment Video

Updated: Sep 10, 2025

ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
07:11

ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

Published on: August 19, 2021

2.6K

LBONet: Supervised Spectral Descriptors for Shape Analysis.

Oguzhan Yigit, Richard C Wilson

    IEEE Transactions on Pattern Analysis and Machine Intelligence
    |August 20, 2025
    PubMed
    Summary
    This summary is machine-generated.

    This study introduces a supervised method to learn task-specific operators for the Laplace-Beltrami operator (LBO). This approach enhances spectral signatures for improved non-rigid shape analysis in various applications.

    More Related Videos

    Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing
    06:25

    Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

    Published on: February 23, 2024

    698
    Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
    06:20

    Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension

    Published on: December 5, 2020

    2.5K

    Related Experiment Videos

    Last Updated: Sep 10, 2025

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis
    07:11

    ARL Spectral Fitting as an Application to Augment Spectral Data via Franck-Condon Lineshape Analysis and Color Analysis

    Published on: August 19, 2021

    2.6K
    Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing
    06:25

    Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

    Published on: February 23, 2024

    698
    Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension
    06:20

    Contrast-Enhanced Subharmonic Aided Pressure Estimation SHAPE Using Ultrasound Imaging with a Focus on Identifying Portal Hypertension

    Published on: December 5, 2020

    2.5K

    Area of Science:

    • Differential Geometry
    • Computer Vision
    • Machine Learning

    Background:

    • The Laplace-Beltrami operator (LBO) is crucial for non-rigid shape analysis due to its invariance under isometric transformations.
    • Its performance degrades with non-isometric deformations, limiting real-world applications.
    • While deep learning excels at feature extraction, spectral signatures remain valuable.

    Purpose of the Study:

    • To develop a supervised framework for learning task-specific operators on manifolds.
    • To adapt the LBO's eigenbasis for improved performance in diverse shape analysis tasks.
    • To enhance established shape descriptors by optimizing the LBO.

    Main Methods:

    • Proposing a supervised learning approach to customize LBO operators.
    • Training task-specific LBO eigenbases.
    • Evaluating optimized LBO on retrieval, classification, segmentation, and correspondence tasks.

    Main Results:

    • Significant improvements in established descriptors like the heat kernel signature.
    • Demonstrated adaptation of the LBO eigenbasis for both global and local learning settings.
    • Validation of the supervised LBO optimization for enhanced shape analysis.

    Conclusions:

    • Supervised learning offers a powerful way to adapt the LBO for specific shape analysis challenges.
    • Optimized LBO significantly boosts performance across multiple computer vision tasks.
    • This method bridges the gap between traditional spectral methods and modern deep learning.