Related Experiment Video
Updated: Sep 10, 2025
07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
529
Unmet Needs and Future Direction for Pulmonary Embolism Interventions
Harshvardhan Zala1, Huseyin Emre Arman2, Saurav Chatterjee3
1Division of Cardiovascular Medicine, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202-3082, USA.
Cardiac Electrophysiology Clinics
|August 20, 2025
Summary
Pulmonary embolism (PE), a common cause of death, originates from deep vein thrombosis. This review examines PE risk, definitions, and effective catheter-based treatments for acute cases.
Area of Science:
- Cardiology
- Vascular Medicine
- Pulmonary Medicine
Background:
- Venous thromboembolism (VTE) commonly affects deep extremity veins.
- Pulmonary embolism (PE), a major VTE type, frequently arises from lower extremity deep vein thrombi.
- PE ranks as the third leading cause of mortality, following myocardial infarction and stroke.
Purpose of the Study:
- To review and define risk stratification for pulmonary embolism.
- To explore current management strategies for acute PE.
- To evaluate the efficacy of various catheter-based treatment options for PE.
Main Methods:
- Literature review of studies on PE risk stratification.
- Analysis of definitions and classifications of PE.
- Examination of treatment guidelines and clinical trial data for acute PE management.
- Assessment of catheter-based interventions for PE.
Main Results:
- Established risk stratification models and diagnostic criteria for PE.
- Detailed discussion on the management pathways for acute PE.
- Comparative analysis of the effectiveness of different catheter-based treatments, including their success rates and complication profiles.
Conclusions:
- Accurate risk stratification is crucial for guiding PE management.
- Catheter-based treatments offer effective therapeutic options for acute PE.
- Further research may refine treatment protocols and improve patient outcomes in PE management.
Related Concept Videos
01:27Pulmonary Embolism III: Nursing Management
38
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
38
01:29Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
44
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
44
01:29Pulmonary Embolism I: Introduction
45
Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
45
01:29Venous Thrombosis III: Interprofessional Care
22
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
22
01:30Pneumonia V: Nursing management and Prevention
2.5K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.5K
01:30Venous Thrombosis IV: Nursing Management
23
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
23