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Are We Getting Better at Achieving Optimal Lumbar Segmental Sagittal Alignment in Complex Adult Spine Deformity
Peter G Passias1, Oluwatobi O Onafowokan1, Renaud Lafage2
1Duke Spine Division, Departments of Neurological and Orthopaedic Surgery, Duke School of Medicine, NC.
Spine
|August 22, 2025
Summary
Surgeons improved lumbar segmental alignment in Adult Spinal Deformity (ASD) surgery over 15 years. However, achieving ideal alignment across all segments remains challenging, indicating areas for future refinement in surgical techniques.
Area of Science:
- Spine surgery and biomechanics.
- Orthopedic research and deformity correction.
Background:
- Adult Spinal Deformity (ASD) management has advanced significantly.
- The impact of these advances on surgical correction of lumbar segmental alignment is not well understood.
Purpose of the Study:
- To investigate the influence of surgical advancements on lumbar segmental alignment in ASD patients.
- To compare alignment outcomes between early and late surgical cohorts.
Main Methods:
- Retrospective multi-center study comparing early (2008-2017) and late (2018-present) ASD surgical cohorts.
- Patients stratified by pelvic incidence (PI) and Roussouly type.
- Segmental and regional alignment analyzed against normative values using statistical comparisons.
Main Results:
- The late cohort showed improved L5-S1 alignment (P=0.001), while the early cohort had better L4-5 alignment (P=0.001).
- Improved alignment correlated with better Oswestry Disability Index (ODI) scores and fewer mechanical complications.
- Both groups had suboptimal L4-S1 and L1-S1 alignment, with the late cohort showing a higher proportion of 'Aligned' patients based on lordosis distribution (15.9% vs. 11%, P<0.001).
Conclusions:
- Surgical techniques have improved lumbar segmental sagittal alignment restoration in ASD patients over the last 15 years.
- Ideal alignment correction is not consistent across all lumbar segments, highlighting opportunities for further surgical optimization.
Keywords:
adult spine deformitylumbar lordosislumbar spinerealignmentsagittal alignmentsegmental alignmentspine deformityvertebral column
