Dual-key cooperatively activated DNA regulator for controlling mitochondria-lysosome interactions

Yang Xiao1, Longyi Zhu1, Songyuan Du1,2

  • 1School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, China.

Nature Communications
|August 22, 2025
PubMed
Summary

Researchers developed a DNA-based platform for precise control over mitochondria-lysosome interactions. This system enables spatiotemporal regulation of cellular processes like mitochondrial fission and autophagy, offering a new tool for cell biology and therapy.

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