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Updated: Sep 10, 2025

Closed Chest Biventricular Pressure-Volume Loop Recordings with Admittance Catheters in a Porcine Model
Published on: May 18, 2021
An Integrated Pressure-Volume Loop and Pulmonary Artery Catheter
M Imran Aslam1, Aleksandra B Gruslova2, Luis A Diaz Sanmartin2
1Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
Abstract:
An admittance technology (AT) pulmonary artery catheter was developed to measure instantaneous right ventricular (RV) pressure-volume loops. Admittance RV volumes were validated in vivo through 10 swine subjected to positive and negative hemodynamic perturbations compared with magnetic resonance imaging and ex vivo RV foam casts. Finite element analysis demonstrated the AT electric field was confined to RV blood volume. RV pressure-volume loops demonstrated anticipated changes in all hemodynamics, and end-diastolic volumes were equal to magnetic resonance imaging and foam casts (P = NS). Increasing RV end-diastolic volumes in response to acute cardiac injury were also measured (P < 0.001). We report validating an AT pulmonary artery catheter in a swine model.
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