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Adolescent Gluteal Cleft Pathologies Not Due to Pilonidal Disease: A Case Series and Diagnostic Algorithm
Pamela Emengo1, Claire Abrajano1, Bill Chiu1
1Division of Pediatric Surgery, Department of Surgery, Stanford University, CA, USA.
Clinical Medicine Insights. Pediatrics
|August 27, 2025
Summary
Adolescent gluteal cleft issues often mimic pilonidal disease but can stem from diverse causes. A new diagnostic algorithm helps differentiate these non-pilonidal pathologies in pediatric patients.
Area of Science:
- Pediatric Surgery
- Adolescent Medicine
- Dermatology
Background:
- Gluteal cleft pathologies in adolescents can be misdiagnosed as pilonidal disease.
- It is crucial to distinguish pilonidal disease from other non-pilonidal conditions affecting the gluteal cleft.
- This study focuses on adolescent patients presenting with non-pilonidal gluteal cleft pathologies.
Purpose of the Study:
- To identify and characterize non-pilonidal diseases presenting in the gluteal cleft of adolescent patients.
- To develop a diagnostic algorithm for differentiating various gluteal cleft pathologies in adolescents.
- To aid clinicians in accurate diagnosis and management of pediatric gluteal cleft conditions.
Main Methods:
- Retrospective review of patients presenting to a pediatric Pilonidal Clinic from January 2019 to December 2023.
- Inclusion criteria: patients requiring work-up for diseases distinct from pilonidal disease.
- Data collected included demographics, clinical work-up, and treatment outcomes.
Main Results:
- Twenty-one adolescent patients with non-pilonidal diagnoses were identified.
- Diagnoses included neurological diseases (4), dermatological conditions (7), inflammatory bowel disease (5), sacral dimples (4), and a sacral pressure ulcer (1).
- Diagnostic decisions were guided by wound characteristics, immobility history, gluteal cleft findings, and clinical symptoms.
Conclusions:
- A practical diagnostic algorithm was developed for differentiating gluteal cleft pathologies in adolescents.
- The algorithm encompasses dermatologic, colorectal, neurologic, and traumatic causes.
- This tool assists in distinguishing non-pilonidal conditions from pilonidal disease in pediatric patients.
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