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Updated: Sep 10, 2025

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Patient-Reported Side Effect Bother: Understanding the Value of the Baseline Report.

Jessica Roydhouse1, Monique Breslin2, Anne Zola3

  • 1Menzies Institute for Medical Research, University of Tasmania, 15-17 Liverpool Street, Hobart, TAS, 7000, Australia. jessica.roydhouse@utas.edu.au.

The Patient
|August 27, 2025
PubMed
Summary

Assessing patient-reported side effect bother using the FACT-GP5 item is crucial for cancer trial tolerability. High bother at baseline was linked to increased early discontinuation risk, though not statistically significant after adjustments.

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