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Safety and Efficacy of Transvaginal Natural Orifice Transluminal Endoscopic (vNOTES) Right Colectomy: A Systematic
Georgia Dimopoulou1, Konstantinos Perivoliotis2, Evangelos Lolis3
1Department of Surgery, "Achillopouleion" General Hospital, 382 22 Volos, Greece.
Abstract:
Background/Objectives: We aim to provide pooled data on the safety and efficacy of Transvaginal Natural Orifice Transluminal Endoscopic (vNOTES) right colectomy. Methods: This systematic review was conducted according to the Cochrane Handbook and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The primary endpoint was the overall complication rate. Quality assessment was based on the NHLBI quality assessment tools. Results: Overall, six studies were included in this review. Overall morbidity rate was 21.9% (95% CI: 10.7-33.2%, p < 0.001), while intraoperative adverse events were noted in 19.9% (p < 0.001) of cases. Mean operation duration was 176.42 (p < 0.001) minutes. Overall hospital stay was 8.68 days (p = 0.002). Conclusions: Our analyses confirm the safety and efficacy of the approach. Given several study limitations, further large-scale and high-quality trials are required.
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