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Published on: July 13, 2019
Central Line-Associated Bloodstream Infections in Pediatrics: A Review
Aarti C Bavare1,2, Catherine E Foster3,4, Amanda L Wollam2
1Division of Critical Care, Department of Pediatrics, Baylor College of Medicine, Houston, Texas.
Central line-associated bloodstream infections (CLABSIs) are a significant concern in pediatric patients with central venous catheters. Evidence-based guidelines have successfully reduced CLABSI rates over the past two decades.
Area of Science:
- Pediatric Infectious Diseases
- Healthcare Epidemiology
- Infection Prevention
Background:
- Central line-associated bloodstream infections (CLABSIs) represent a major healthcare-associated infection in pediatric patients requiring central venous catheters.
- These infections pose significant risks to both hospitalized and non-hospitalized children.
Purpose of the Study:
- To provide a comprehensive review of CLABSIs in pediatric populations.
- To detail the definition, pathogenesis, risk factors, prevention strategies, and treatment principles for pediatric CLABSIs.
Main Methods:
- Review of existing literature and evidence-based guidelines.
- Synthesis of information from professional societies like the CDC and NHSN.
- Analysis of prevention and management strategies over the last two decades.
Main Results:
- Significant reductions in CLABSI rates have been achieved through guideline implementation.
- Evidence-based practices have demonstrably improved patient outcomes.
- The review consolidates current knowledge on CLABSI prevention and treatment.
Conclusions:
- CLABSI prevention in pediatric patients has advanced significantly due to standardized guidelines.
- Continued adherence to evidence-based practices is crucial for minimizing CLABSI incidence.
- This review serves as a resource for understanding and managing CLABSIs in children.
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