Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.2K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.2K
Effects of EDTA on End-Point Detection Methods01:18

Effects of EDTA on End-Point Detection Methods

344
Different methods, such as visual observance of metal-ion indicators, spectroscopic techniques, and potentiometric methods, can determine the endpoint of an EDTA titration.
In the visual method, metal-ion indicators (metallochromic dyes), which have distinct colors in their free and complex forms, are added to the mixture to signal the titration's end point. They form stable complexes with metal ions, but these complexes are weaker than the corresponding metal–EDTA complexes. As a...
344
NMR Spectrometers: Resolution and Error Correction01:14

NMR Spectrometers: Resolution and Error Correction

774
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
774

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-Temporal-Resolution Monitoring of Creatine and Phosphocreatine Dynamics in Skeletal Muscle Using Ultrafast Z-Spectroscopy (UFZ) CEST MRI at 3T.

Magnetic resonance in medicine·2026
Same author

Rapid Tissue-CSF Water Exchange in the Human Brain Revealed by Magnetization Transfer Indirect Spin Labeling.

Magnetic resonance in medicine·2026
Same author

Accelerating CEST MRI through complementary undersampling and multi-offset transformer reconstruction.

Communications engineering·2026
Same author

Modeling the age-specific incidence of mild cognitive impairment incorporating the time-varying relationship of Alzheimer's disease biomarkers over 28 years.

Journal of Alzheimer's disease : JAD·2025
Same author

Accelerated Chemical Exchange Saturation Transfer Imaging With Deep Unrolling Networks and Synthetic Brain Tumor Datasets.

Magnetic resonance in medicine·2025
Same author

Deep-learning-based HER2 status assessment from multimodal breast cancer data predicts neoadjuvant therapy response.

Nature biomedical engineering·2025

Related Experiment Video

Updated: Sep 9, 2025

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
10:23

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy

Published on: June 23, 2023

2.1K

Evaluating the effectiveness of distortion self-correction for CEST-EPI.

Yang Liu1,2, Se Weon Park1,2, Lok Hin Law1,2

  • 1Department of Biomedical Engineering, City University of Hong Kong, Hong Kong, China.

Magnetic Resonance in Medicine
|August 30, 2025
PubMed
Summary

This study introduces Distortion Self-Correction (DISC) for Chemical Exchange Saturation Transfer (CEST) Echo-Planar Imaging (EPI). DISC effectively corrects geometric distortions in CEST-EPI at 3T, improving image quality and quantification.

Keywords:
CESTEPIdistortionself‐correctionΔB0 map

More Related Videos

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

14.8K
Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

895

Related Experiment Videos

Last Updated: Sep 9, 2025

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy
10:23

Equipment Setup and Artifact Removal for Simultaneous Electroencephalogram and Functional Magnetic Resonance Imaging for Clinical Review in Epilepsy

Published on: June 23, 2023

2.1K
Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example
08:45

Mapping Cortical Dynamics Using Simultaneous MEG/EEG and Anatomically-constrained Minimum-norm Estimates: an Auditory Attention Example

Published on: October 24, 2012

14.8K
Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process
07:00

Electrically Evoked Stapedius Reflex Measurements in Cochlear Implantation and Its Application in the Postoperative Fitting Process

Published on: June 21, 2024

895

Area of Science:

  • Magnetic Resonance Imaging
  • Biomedical Engineering
  • Medical Physics

Background:

  • Echo-Planar Imaging (EPI) is a rapid MRI sequence but susceptible to geometric distortions from B0 field inhomogeneity.
  • Chemical Exchange Saturation Transfer (CEST) MRI provides functional and metabolic information but often requires distortion correction for accurate analysis.

Purpose of the Study:

  • To evaluate the effectiveness of a novel Distortion Self-Correction (DISC) strategy for CEST-EPI.
  • To utilize ΔB0 maps derived from single-shot CEST-EPI for intrinsic geometric distortion correction.

Main Methods:

  • A ΔB0 map was generated from Z-spectra of CEST-EPI without additional scans.
  • The proposed DISC strategy was applied to correct geometric distortions in CEST-EPI.
  • The method was validated on phantoms and in vivo across 3T and 11.7T MRI systems.
  • Quantitative assessment used Structural Similarity Index Measure (SSIM) and visual comparison.

Main Results:

  • DISC-CEST-EPI demonstrated improved SSIM and spatial consistency compared to standard CEST-EPI at 3T.
  • At 11.7T, DISC-CEST-EPI showed comparable performance to established field-mapping techniques for specific CEST contrasts.

Conclusions:

  • DISC-CEST-EPI effectively corrects geometric distortions in CEST-EPI at 3T, enhancing image quality and quantification.
  • This technique shows promise for improving diagnostic accuracy in low-field MRI applications.
  • Further development is needed to optimize DISC performance at ultra-high fields (11.7T).