Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Multimodal Sensor-Based Self-Supervised Learning Framework for Low-Noise System State Prediction and Anomaly Detection.

Sensors (Basel, Switzerland)·2026
Same author

Synergistic efficacy of radiotherapy and immunotherapy enhances clinical outcomes in patients with advanced non-small cell lung cancer.

Discover oncology·2026
Same author

A predictive model for high-quality blastocyst formation using Day 3 morphological scores in women of advanced maternal age.

BMC pregnancy and childbirth·2026
Same author

Inflammation-driven mitochondrial dysfunction and ROS accumulation orchestrate pulmonary fibrotic remodeling in sepsis.

Redox biology·2026
Same author

Prognostic impact of anatomic site in pheochromocytomas and paragangliomas: a population-based cohort study.

European journal of endocrinology·2026
Same author

Non-specific low back pain prevalence and associated factors among Chinese people aged 60 years and older: a cross-sectional study.

Frontiers in public health·2026
Same journal

Performance Evaluation of Highly Uniform Astragalus Polysaccharide/Silk Fibroin Microspheres Fabricated via Microfluidics as Biodegradable Fillers: Collagen Regeneration and Tissue Reaction.

Journal of biomedical materials research. Part A·2026
Same journal

Combining Supramolecular and Covalent Chemistry to Form Reinforced Fibrillar Network Hydrogels From Fibrinogen Derivatives.

Journal of biomedical materials research. Part A·2026
Same journal

Bioactive-Loaded Detachable Crosslinked Hyaluronic Acid Microneedles: Structural Validation and Clinical Anti-Wrinkle Efficacy.

Journal of biomedical materials research. Part A·2026
Same journal

Tunable Sol-Gel Transition in Poloxamer Blends for Injectable Osteoarticular Applications.

Journal of biomedical materials research. Part A·2026
Same journal

Development and Evaluation of Polyvinyl Alcohol/Carboxymethyl Chitosan Hydrocolloid Incorporating Cynodon dactylon Extract and Zinc Oxide Nanoparticle for Bedsore Healing in a Wistar Rat Model.

Journal of biomedical materials research. Part A·2026
Same journal

Engineering Bone-Targeted LNP Delivery of Anti-Sclerostin Antibody mRNA for the Treatment of Osteoporosis.

Journal of biomedical materials research. Part A·2026
See all related articles

Related Experiment Video

Updated: Sep 9, 2025

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
06:36

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

9.7K

3D-Printed Precision Porous Scaffolds Promote Healing In Vivo.

Guoyao Chen1,2, Sharon Creason2,3, Ningjing Chen2,4

  • 1Department of Chemical Engineering, University of Washington, Seattle, Washington, USA.

Journal of Biomedical Materials Research. Part A
|August 30, 2025
PubMed
Summary
This summary is machine-generated.

High-resolution 3D-printed porous scaffolds with 40μm cubical pores effectively reduce foreign body reactions and promote tissue healing. These advanced scaffolds show promise for regenerative medicine applications in both soft and hard tissue repair.

Keywords:
3D printingbiomaterialsforeign body reactionporous scaffolds

More Related Videos

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.5K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Related Experiment Videos

Last Updated: Sep 9, 2025

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
06:36

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

9.7K
Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures
05:52

Core/shell Printing Scaffolds For Tissue Engineering Of Tubular Structures

Published on: September 27, 2019

9.5K
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
09:35

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Published on: September 11, 2015

9.8K

Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Regenerative Medicine

Background:

  • Precision porous scaffolds are crucial for tissue engineering and regenerative medicine.
  • Vat photopolymerization 3D printing can create scaffolds with 40μm interconnected cubical pores.
  • Evaluating cellular responses and foreign body reaction (FBR) to these scaffolds is essential.

Purpose of the Study:

  • To preliminarily evaluate cellular responses and FBR to 3D-printed scaffolds with 40μm cubical pores.
  • To compare these scaffolds against template-fabricated spherical pores and non-porous controls.
  • To demonstrate the pro-healing properties of high-resolution 3D-printed scaffolds.

Main Methods:

  • Fabrication of porous scaffolds with 40μm cubical pores using vat photopolymerization 3D printing.
  • Comparison with template-fabricated spherical pores and non-porous slabs.
  • Evaluation of cellular responses and FBR.

Main Results:

  • Porous scaffolds, irrespective of pore geometry, demonstrated superior performance compared to non-porous structures.
  • Reduced FBR, enhanced tissue regeneration, and increased vascularization were observed in porous scaffolds.
  • This study is the first to show the pro-healing potential of 3D-printed 40μm cubical pore scaffolds.

Conclusions:

  • 3D-printed porous scaffolds effectively mitigate FBR and promote tissue healing.
  • These scaffolds hold significant potential for advancing patient-specific therapies in regenerative medicine.
  • Applications include repair of soft tissues (brain, blood vessels) and hard tissues (bone).