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Reporting the Pooled Last Follow-up Musculoskeletal Tumor Society Score Underestimates Functional Improvements Seen
Alysia K Kemp1, Theresa Nalty, Grant McChesney
1From the University of Texas MD Anderson Cancer Center, Department of Orthopaedic Oncology, Houston, USA (Dr. Kemp, Dr. Nalty, Dr. McChesney, Dr. Geng, Dr. Patel, Dr. Lewis, and Dr. Bird).
The pooled last follow-up method for reporting Musculoskeletal Tumor Society (MSTS) scores underestimates functional outcomes. Longitudinal time-based reporting offers a more accurate assessment of MSTS functional improvements over time.
Area of Science:
- Orthopaedic Oncology
- Functional Outcome Assessment
Background:
- The Musculoskeletal Tumor Society (MSTS) score is the standard functional outcome tool in Orthopaedic Oncology.
- Current reporting methods lack standardized recommendations, creating a knowledge gap.
Purpose of the Study:
- To systematically review MSTS score reporting methodologies.
- To compare pooled last follow-up versus longitudinal time-based reporting of MSTS scores.
Main Methods:
- Systematic review of over 300 articles reporting MSTS scores.
- Paired t-tests comparing pooled last follow-up MSTS scores with longitudinal time-based scores from institutional data.
Main Results:
- 91.6% of studies used pooled last follow-up MSTS scores.
- Pooled scores underestimated MSTS scores at 1 and 3 years post-surgery (P < 0.0001 and P = 0.0047).
- Functional improvements in MSTS domains stabilized around 1.8 years post-surgery.
Conclusions:
- The pooled last follow-up method inaccurately represents long-term functional outcomes.
- Longitudinal time-based reporting provides a more precise evaluation of functional recovery in Orthopaedic Oncology patients.
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