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Analytical Geometry Description, Clinical Node Distribution, and Geometric Performance of ZAP-X and Its Comparison
Borja Aguilar1,2, Vânia Dias1, Enrique Pascual2
1Medical Physics Department, Mercurius Health, Lisbon, PRT.
Cureus
|September 2, 2025
Summary
The ZAP-X radiosurgery system offers superior beam coverage compared to Gamma Knife. Its advanced design achieves 71% theoretical geometric efficiency and 39% clinical performance, enhancing targeted radiation delivery.
Area of Science:
- Medical Physics
- Neurosurgery
- Radiation Oncology
Background:
- Radiotherapy increasingly utilizes specialized devices for precise treatment delivery.
- The ZAP-X system is a radiosurgery device with a complex geometric design for targeted radiation.
- Minimizing radiation dose to surrounding healthy brain tissue is a key goal in radiosurgery.
Purpose of the Study:
- To provide a geometric description of the ZAP-X gyroscopic system.
- To analyze the theoretical and clinical geometric efficiency of the ZAP-X.
- To compare the ZAP-X's geometric performance with the Gamma Knife system.
Main Methods:
- Analytical geometric description of the ZAP-X gyroscopic system.
- Calculation of theoretical geometric efficiency based on gimbals and solid angle coverage.
- Determination of clinical geometric performance considering Treatment Planning System (TPS) limitations.
- Comparison of ZAP-X geometric efficiency (71% theoretical, 39% clinical) with Gamma Knife (31% clinical).
Main Results:
- The ZAP-X system achieves a maximum theoretical geometric efficiency of 71% solid angle coverage.
- Clinical geometric performance of ZAP-X is 39%, exceeding Gamma Knife's 31%.
- The ZAP-X offers greater beam coverage around the patient's head compared to existing systems.
Conclusions:
- The ZAP-X radiosurgery system demonstrates superior geometric efficiency and clinical performance.
- Its design allows for precise, targeted radiation delivery with reduced impact on normal brain tissue.
- The ZAP-X represents an advancement in radiosurgery technology, offering enhanced treatment capabilities.

