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Statistical Significance

Statistical Significance

Once data is collected from both the experimental and the control groups, a statistical analysis is conducted to find out if there are meaningful differences between the two groups. A statistical analysis determines how likely any difference found is due to chance (and thus not meaningful). In psychology, group differences are considered meaningful, or significant, if the odds that these differences occurred by chance alone are 5 percent or less. Stated another way, if we repeated this...

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Estimating a minimum clinically important difference for the Developmental Behaviour Checklist - parent report.

Daniel L Sutherland¹, Emma L Taylor^1,2, Kylie M Gray^2,3

¹Centre for Research in Intellectual and Developmental Disabilities (CIDD), University of Warwick, Coventry, United Kingdom.

Frontiers in Psychiatry

|September 2, 2025

Summary

This study estimated the Minimum Clinically Important Difference (MCID) for the Developmental Behaviour Checklist, parent-report (DBC-P). Findings provide benchmarks for interpreting changes in behavioral and emotional problems in children with intellectual disabilities.

Keywords:

Developmental Behavior Checklist (DBC)autism intellectual disabilities meta analysis minimum clinically important difference (MCID)

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Area of Science:

Child and Adolescent Psychiatry
Developmental Psychology
Intellectual Disability Research

Background:

Evaluating intervention effectiveness requires understanding meaningful outcome changes.
The Developmental Behaviour Checklist, parent-report (DBC-P) measures behavioral and emotional problems in children and adolescents with intellectual disabilities.

Purpose of the Study:

To estimate the Minimum Clinically Important Difference (MCID) for the DBC-P.
To provide benchmarks for interpreting DBC-P score changes.

Main Methods:

Distribution-based estimates were derived from a meta-analysis of 21 intervention evaluations using the DBC-P.
Anchor-based estimates were obtained from 10 parent carers and 21 professionals using case scenarios.

Main Results:

Meta-analyses showed average DBC total raw score decreases of 3.01-4.73 in RCTs and 9.16 in pre-post designs.
Parent carers reported a median MCID of 6 (IQR 4-7), while professionals reported a median MCID of 8 (IQR 5-14).

Conclusions:

Findings contextualize DBC-P score changes relative to other interventions and stakeholder perspectives.
The choice of MCID value depends on the prioritized factors for a given intervention.