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Minimally Invasive Techniques for Nasal Valve Dysfunction: A Systematic Review and Meta-Analysis.
Guled M Jama1, Filippo Cainelli2, Luiza Farache Trajano3
1Department of Rhinology and Facial Plastic Surgery, Charing Cross Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.
Facial Plastic Surgery : FPS
|September 2, 2025
Summary
Minimally invasive treatments for nasal valve dysfunction (NVD) offer significant symptom relief and are well-tolerated. These office-based options provide durable improvements, presenting viable alternatives to traditional surgery for nasal obstruction.
Area of Science:
- Otolaryngology
- Minimally Invasive Surgery
- Rhinology
Background:
- Nasal valve dysfunction (NVD) is a common cause of nasal obstruction, impacting patient quality of life.
- Office-based interventions are emerging as alternatives to traditional surgery for NVD.
- Comparative safety and efficacy of these new treatments require further evaluation.
Purpose of the Study:
- To systematically review and meta-analyze the safety and efficacy of minimally invasive office-based interventions for NVD.
- To assess patient-reported outcomes, including Nasal Obstruction Symptom Evaluation (NOSE) and Visual Analog Scale (VAS) scores.
- To compare different minimally invasive techniques for NVD treatment.
Main Methods:
- Systematic review and meta-analysis following PRISMA guidelines.
- Searched four databases (PubMed, Scopus, Cochrane Library, Ovid) for studies from 2005-2025.
- Included 15 studies (546 patients) evaluating temperature-controlled radiofrequency (TCRF), bioabsorbable implants, suturing, and stenting.
Main Results:
- All evaluated interventions (TCRF, implants, suturing) showed statistically significant improvements in NOSE and VAS scores.
- Temperature-controlled radiofrequency (TCRF) demonstrated a weighted mean difference (WMD) of -44.68 in NOSE scores (p < 0.001).
- Improvements were sustained for 3-48 months, with mild and transient adverse events.
Conclusions:
- Minimally invasive techniques for NVD provide significant, clinically important, and durable symptom relief.
- These interventions have favorable safety profiles and may be suitable alternatives to traditional surgery.
- Future research should focus on randomized controlled trials and standardized outcome measures.
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