[Limiting stress activation of the adrenergic and pituitary-adrenal systems by alpha-tocopherol]

alpha-Tocopherol reduced distinctly the intensity and duration of the stress reaction. Preadministration of alpha-tocopherol into animals before stress prevented the corticosterone elevation as well as the catecholamine decrease in heart muscle and adrenal glands; at the same time, the vitamin reduced 2-fold the duration of eosinopenia. Besides, the intensity of NA-3N neuronal uptake was twice increased in these tissues.