Multivisceral Resection for Locally Advanced Colon Cancer: Clinical and Treatment Characteristics Based on Final...

Area of Science:

• Surgical Oncology
• Gastrointestinal Surgery
• Colorectal Cancer Research

Background:

• Radical resection is crucial for long-term survival in colon cancer patients.
• Locally advanced colon cancer often necessitates multivisceral resection for complete tumor removal (R0 resection).

Purpose of the Study:

• To analyze tumor characteristics, surgical approaches, and outcomes of multivisceral resections in colon cancer.
• To evaluate early results and final pathological findings in patients undergoing this extensive surgery.

Main Methods:

• Retrospective analysis of consecutive colon cancer patients who underwent multivisceral resection (January 2018 - January 2025).
• Evaluation of clinical data, surgical procedures, postoperative complications, and pathological staging (pT3, pT4a, pT4b).
• Grouping patients based on TNM staging and pathological tumor differentiation.

Main Results:

• Multivisceral resection was performed in 8.47% (82/968) of colon cancer surgeries.
• pT4 tumors (74.4%) were more prevalent than pT3 (25.6%), with a high proportion of pT4b (52.4%).
• Commonly resected organs included small bowel, bladder, genital organs, and abdominal wall. pT4b tumors showed higher rates of poor differentiation and lymphovascular/perineural invasion. Severe complications occurred in 7.31%.

Conclusions:

• Multivisceral resection is a relatively safe and effective procedure for radical treatment of advanced colon cancer.
• High-volume tertiary centers with experienced surgical teams are essential for successful outcomes in these complex cases.
• This approach provides a safe solution for patients requiring extensive surgery for advanced abdominal malignancies.