Related Experiment Video
Updated: Jan 18, 2026

18:50
Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
14.0K
Exoscopic Keyhole Clipping of Unruptured Middle Cerebral Artery Aneurysms Using Multiple 4K 3-dimensional Monitors
Shingo Toyota1, Tomoaki Murakami1, Kosei Okochi1
1Department of Neurosurgery, Kansai Rosai Hospital.
Neurologia Medico-Chirurgica
|September 7, 2025
Summary
Exoscopic keyhole clipping using an ORBEYE exoscope and 4K 3D monitors is safe and effective for unruptured middle cerebral artery aneurysms. This technique is not inferior to traditional microscopic approaches, facilitating a potential shift for neurosurgeons.
Area of Science:
- Neurosurgery
- Minimally Invasive Techniques
- Medical Technology
Background:
- Traditional surgical microscopy for aneurysm clipping presents visual limitations.
- Advancements in exoscopic technology offer potential for enhanced visualization in neurosurgery.
Purpose of the Study:
- To evaluate the safety and efficacy of exoscopic keyhole clipping for unruptured middle cerebral artery aneurysms.
- To compare exoscopic clipping with traditional microscopic techniques.
Main Methods:
- Nineteen patients underwent exoscopic keyhole clipping using the ORBEYE exoscope and multiple 4K 3D monitors.
- A historical control group of 21 patients treated with surgical microscopy was used for comparison.
- Key outcomes included procedure success, aneurysm diameter, craniotomy size, procedure duration, blood loss, and indocyanine green dose.
Main Results:
- All exoscope procedures were successful.
- No significant differences were observed in aneurysm diameter, craniotomy size, procedure duration, or blood loss between groups.
- The exoscope group showed a significantly lower mean indocyanine green dose.
Conclusions:
- Exoscopic keyhole clipping for unruptured middle cerebral artery aneurysms is safe, efficient, and comparable to microscopic clipping.
- The use of an exoscope with multiple 4K 3D monitors presents no major barriers for neurosurgeons transitioning from microscopy.

