First Report of 68 Ga-FAPI PET/CT Imaging in Fallopian Tube Cancer: Implications for Diagnosis and Staging

We report the case of a 47-year-old woman who presented with left inguinal swelling; the biopsy of which showed high-grade serous adenocarcinoma. 68 Ga-FAPI PET/CT revealed a tracer-avid lesion in the left adnexal region and an enlarged left inguinal nodal mass (site of biopsy). Multiple focal lesions were also seen at the hepatic dome, along the falciform ligament and at the right lateral abdominal wall, suspicious for peritoneal/metastatic deposits. The patient received 3 cycles of neoadjuvant chemotherapy, followed by interval debulking surgery. Tumor was seen in the left fallopian tube, but not in the ovaries. 68 Ga-FAPI PET/CT provides better lesion localization due to a higher tumor-to-background ratio.