[Pathomorphology of Kaposi's sarcoma]

Chaotic angiogenesis and permanent presence of spindle cells with a variable degree of nuclear atypia in the nodular aid tumourous foci represent important diagnostic criteria of Kaposi's sarcoma (KS). At early stages or, on the contrary, in the persistent lesions morphological picture is not sufficiently characteristic and the diagnosis cannot be established on the basis of histological examination only; evaluation of the clinical and morphological data and repeated biopsy are necessary in such cases. The degree of manifestation of a spindle-cell component and the degree of its anaplasia are not determining factors in the prognosis of disease.