Photo/electro-mediated radical cascade functionalization/cyclization reactions involving N-acryloyl 2-aryl
Fatemeh Doraghi1, Amirali Abbasi2, Nooshin Zomorodiyan3
1Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences Tehran Iran momahdavi@tums.ac.ir.
Abstract:
Indolo/benzimidazo-isoquinoline scaffolds are frequently found in many natural products, pharmaceuticals, and organic materials. Owing to their prominent properties, in recent years, numerous studies have been performed on the synthesis of indolo/benzimidazo-isoquinoline derivatives via photo-, and electro-promoted functionalization/cyclization reactions of N-acryloyl 2-aryl indoles/benzimidazoles. In this review, we describe these fascinating transformations and discuss their mechanistic insights.
More Related Videos
06:34Synthesis of Antiviral Tetrahydrocarbazole Derivatives by Photochemical and Acid-catalyzed C-H Functionalization via Intermediate Peroxides CHIPS
Published on: June 20, 2014
09:12[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Related Concept Videos
Radical Reactivity: Intramolecular vs Intermolecular
Electrophilic Aromatic Substitution: Friedel–Crafts Acylation of Benzene
Benzene to 1,4-Cyclohexadiene: Birch Reduction Mechanism
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Radical Reactivity: Nucleophilic Radicals
Thermal and Photochemical Electrocyclic Reactions: Overview
