Related Experiment Video
Updated: Jan 18, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Prognostic Value of Biomarkers in Chronic Obstructive Pulmonary Disease: A Comprehensive Review
Yunpeng Xu1, Lei Zhang1, Lei Zhu2
1The First Clinical Medical College of Lanzhou University, Lanzhou, People's Republic of China.
Biomarkers and multimodal data improve Chronic Obstructive Pulmonary Disease (COPD) prognosis prediction. This review explores their use for personalized COPD management and clinical application.
Area of Science:
- Pulmonary Medicine
- Biomarker Discovery
- Respiratory Research
Background:
- Chronic Obstructive Pulmonary Disease (COPD) presents significant heterogeneity and complexity.
- Traditional clinical assessments face challenges in prognostic prediction and personalized management for COPD patients.
Purpose of the Study:
- To review key biomarkers for COPD prognosis.
- To discuss the application and potential of multi-biomarker models and multimodal data integration.
- To evaluate the translational value of these approaches in clinical practice for precision COPD management.
Main Methods:
- Narrative review of scientific literature.
- Systematic discussion of prognostic biomarkers in COPD.
- Analysis of multi-biomarker prediction models and multimodal data integration strategies.
Main Results:
- Biomarker exploration offers new avenues for precise COPD evaluation.
- Multi-biomarker models and multimodal data integration enhance prognostic accuracy and reliability.
- These integrated strategies show significant potential for personalized COPD management.
Conclusions:
- Biomarkers and integrated data strategies are crucial for advancing precision medicine in COPD.
- Further research and clinical validation are needed to maximize their translational value.
- This review provides a scientific basis for improved COPD prognosis and patient care.
More Related Videos
02:09Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
Published on: April 12, 2024
10:03Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Related Concept Videos
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-I: Introduction
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Chronic Obstructive Pulmonary Disease-V: Management
Smoking Cessation
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD: