Food-Grade Liposome-Loaded Delivery Systems: Current Trends and Future Perspectives

Area of Science:

• Food Science and Technology
• Materials Science
• Biotechnology

Background:

• Liposomes, with their amphiphilic nature, are effective carriers for hydrophilic and lipophilic food bioactives.
• Challenges with liposomes include poor stability, leakage, and environmental sensitivity in aqueous systems.

Purpose of the Study:

• To review the structure, preparation, and application of liposomes in food.
• To explore hybrid liposome systems for enhanced delivery of food ingredients.
• To emphasize advancements in food-grade hybrid liposome technology.

Main Methods:

• Comprehensive literature review on liposome encapsulation and hybrid systems.
• Analysis of incorporation methods of liposomes into various matrices (nanofibers, particles, hydrogels, etc.).
• Evaluation of functional performance and delivery efficiency of hybrid systems.

Main Results:

• Hybrid systems significantly improve structural integrity and protection of encapsulated compounds.
• Incorporation into matrices enhances liposome stability during processing and storage.
• Hybrid systems demonstrate extended-release profiles and versatile food applications.

Conclusions:

• Hybrid liposome systems offer synergistic advantages over conventional liposomes for food applications.
• These systems enhance bioavailability and stability of key food ingredients.
• Hybrid liposomes represent a promising approach for developing next-generation functional foods with improved health benefits and shelf life.