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Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
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Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
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The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
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Updated: Jan 17, 2026

Introduction of Intracapsular Rotary-cut Procedures IRCP: A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation
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Cervical Adenofibroma: A Rare Cause for Postmenopausal Bleeding.

Navdeep Kaur1, Akanksha Agarwal2, Bharti Sharma3

  • 1Department of Obstetrics and Gynaecology, PGIMER Satellite Centre, Sangrur, Punjab, India.

Journal of Mid-Life Health
|September 15, 2025
PubMed
Summary

Cervical adenofibroma, a rare benign tumor, requires careful histopathological examination. Despite its benign nature, it can exhibit aggressive behavior, necessitating accurate diagnosis to exclude malignancy.

Area of Science:

  • Gynecologic Pathology
  • Oncology
  • Reproductive Medicine

Background:

  • Cervical adenofibroma is an exceptionally rare benign Mullerian mixed tumor.
Keywords:
Adenofibromaadenosarcomacervixhistopathologyimmunohistochemistrypolyp

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  • It comprises both benign epithelial and mesenchymal tissues.
  • The WHO 2020 classification omits adenofibroma as a distinct entity.