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Updated: Jan 6, 2026

Forming, Confining, and Observing Microtubule-Based Active Nematics
Published on: January 13, 2023
Active sorting to boundaries in active nematic-passive isotropic fluid mixtures
Saraswat Bhattacharyya1, Julia M Yeomans1
1Rudolf Peierls Centre for Theoretical Physics, Parks Road, University of Oxford, OX1 3PU, UK. julia.yeomans@physics.ox.ac.uk.
Abstract:
We use a two-fluid model to study a confined mixture of an active nematic fluid and a passive isotropic fluid. We find that an extensile active fluid preferentially accumulates at a boundary if the anchoring is planar, whereas its boundary concentration decreases for homeotropic anchoring. These tendencies are reversed if the active fluid is contractile. We argue that the sorting results from gradients in the nematic order, and show that the behaviour can be driven by either imposed boundary anchoring or spontaneous anchoring induced by active flows. Our results can be tested by experiments on microtubule-kinesin motor networks, and may be relevant to sorting to the boundary in cell colonies or cancer spheroids.
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