Perfluorodecalin Toxicity Following Retinal Autograft Surgery in a Case With Chronic Recurrent Large Macular Hole

In cases with chronic recurrent large macular holes (MH), retinal autograft can be used to close the MH and perfluorocarbon liquids can be left in the eye for a short time to stabilize the graft. However, there are some cases reported in the literature regarding retinal toxicity due to the use of perfluorocarbon liquids as tamponade in vitreo-retinal surgery. This case report presents a 49-year-old patient with chronic recurrent large MH despite undergoing vitrectomy and internal limiting membrane peeling surgery 8 years prior. Retinal autograft was used to close the MH and stabilization of the autograft was achieved with short-term perfluorodecalin liquid tamponade. However, after the removal of perfluorodecalin fluid, widespread retinal toxicity developed in the macula.