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Passenger Lymphocyte Syndrome Presenting With Severe Refractory Thrombocytopenia After Transplantation: A
Emilee E Larson1, Carlos Aravena2, Deepika P Kulkarni2
1Department of Surgery, Vanderbilt University Medical Center, Section of Surgical Sciences, Division of Kidney & Pancreas Transplantation, Nashville, Tennessee, USA.
Abstract:
Passenger lymphocyte syndrome (PLS) is an immune-mediated complication that can occur following solid organ transplantation, resulting from the transfer of donor-derived lymphocytes that produce alloantibodies targeting recipient antigens. We report a case series of PLS presenting as severe refractory thrombocytopenia in multiple recipients of solid organ transplantation from a single donor.
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