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Reducing translational science roadblocks to disability research.

Karen Bonuck1, Ariel Fishman2

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Summary

People with disabilities (PWDs) face health disparities. Translational science principles and the D2/R3 project address researcher roadblocks to improve inclusion and reduce health inequities for PWDs.

Keywords:
Clinical and Translational Science AwardsDisabilityNational Institutes of Health designationdevelopmental disabilityhealth disparity population

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Area of Science:

  • Translational science
  • Health disparities research
  • Disability inclusion

Background:

  • People with disabilities (PWDs) experience significant health disparities and reduced access to quality healthcare.
  • The National Institutes of Health (NIH) recognized PWDs as a health disparities population in 2023.
  • Understanding factors contributing to PWDs' exclusion from research is crucial for addressing these disparities.

Purpose of the Study:

  • To apply translational science (TS) principles to overcome barriers in reducing health disparities for PWDs.
  • To analyze factors contributing to PWDs' exclusion from research and their reflection in NIH designation reports.
  • To introduce the D2/R3 project as a TS solution targeting researcher-related obstacles to PWD inclusion.

Main Methods:

  • Literature review on PWDs' exclusion from research.
  • Analysis of background reports informing the NIH designation of PWDs as a disparity population.
  • Description of the D2/R3 mixed-methods study targeting research teams' knowledge, attitudes, biases, and perceptions.

Main Results:

  • Identified specific factors contributing to PWDs' underrepresentation in research.
  • Demonstrated how TS principles can guide the implementation of the NIH designation.
  • The D2/R3 project aims to address researcher-level barriers to PWD inclusion.

Conclusions:

  • Translational science offers a framework for addressing health disparities among PWDs.
  • Overcoming researcher roadblocks is essential for increasing the participation of PWDs in studies.
  • The D2/R3 project provides a targeted TS approach to enhance research inclusivity for PWDs, particularly those with developmental disabilities.